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"Would you listen to this! Blame it on the little guy! How original! He must've read the schedule wrong with his ONE EYE!"
Michael "Mike" Wazowski is the deuteragonist in Monsters, Inc. and the protagonist in its prequel Monsters University. He is a light green, spherical monster with one large green eye, two small horns on his head, and thin arms and legs attached to either side of his torso.
In the first film, Mike is Sulley's best friend and working partner at Monsters, Inc.. He supports Sulley about being the number one scarer, and both are enemies of Randall Boggs. He is also Celia Mae's boyfriend and seems to be watched at by Roz who awaits for his paperwork. While at Harryhausen's for Celia's birthday, Sulley appeared out of nowhere to tell Mike that he had lead a human girl into the monster world. Putting her into a Monsters, Inc. gym bag, Sulley tried to show him, but the human girl got out of the bag and wreaked havoc all over the restaurant. The two secretly took her out before the CDA found her and disinfected the entire restaurant.
Mike reappeared in the prequel, Monsters University, as the protagonist. He looks smaller and wears a retainer.
Mike Wazowski is first seen as an elementary student attending Ms. Graves' class visiting Monsters, Inc. as part of a field trip. During the field trip, Mike tries to get a look at the scare floor but the other students push him aside, telling him he doesn't belong there. Mike walks past the safety line and follows a scarer named Frightening Frank McCay into the Human World. Mike watches Frank scare a child then follows him back through the door. Frank is not only surprised but impressed with Mike for sneaking in unnoticed, giving him his Monsters University cap. This incident spurs Mike to become a scarer and attend MU.
Source: Pixar.Wikia.com